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DOI: Nagane M, Kanai E, Shibata Y, Shimizu T, Yoshioka C, Maruo T, et al

A study published in The New England Journal of Medicine showed that male participants over 60 years old, who took hGH for six months gained on average 8.8% lean body mass and lost 14% fat mass

In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )